RECENT ADVANCEMENTS IN NANOPARTICLE-MEDIATED IMMUNOTHERAPY FOR CANCER TREATMENT: A REVIEW

GAYATHRI PRIYADARSHINI, B.Tech., VIT Vellore

Cancer presents a formidable challenge due to its complex cellular alterations and diverse molecular profiles, often leading to treatment resistance and significant morbidity. Traditional therapies such as surgery, chemotherapy, and radiotherapy, while foundational, frequently encounter limitations including metastasis, recurrence, and systemic toxicity (Koyande et al., 2022). Immunotherapy has emerged as a transformative approach by leveraging the body's immune system to target and combat cancer cells effectively. Strategies like immune checkpoint inhibitors and CAR-T cell therapy have demonstrated substantial clinical success, notably in achieving prolonged remission in various malignancies. The approval of ipilimumab for metastatic melanoma stands as a landmark achievement in this field (Fan et al., 2023).

ANALYSIS OF THE CURRENT BAIL JURISPRUDENCE IN INDIA WITH EMPHASIS ON JUDICIAL INTERPRETATION ESPECIALLY IN TERROR LAW

GAURI JADHAV, B.A. LL.B (Hons.), Symbiosis Law School

The aim of arresting and detaining the accused is to ensure they appear for the trial and, if convicted, for sentencing. However, if their presence at trial can be reasonably guaranteed without arrest and detention, it would be unjust to deprive them of liberty during legal proceedings. Thus, bail provisions are designed to secure the accused’s presence at trial without unduly infringing on their freedom. In the contemporary criminal jurisprudence for bail, a dilemma that often comes up is that if bail is granted liberally to next to everyone, there would essentially remain no credibility to the law enforcement. On the other hand, if bail is granted absolutely conservatively, there shall occur cases where guiltless persons shall languish in jail for no fault of theirs; only to be ultimately acquitted. Cases where bail is being denied solely on the ground of seriousness of offence and where other factors are overlooked, imply that it is being denied as a matter of punishment, even before the trial has begun.

TRADE TENSIONS: NAVIGATING DISPUTES AND SANCTIONS IN GLOBAL MARKETS

BIMISHA BORTHAKUR, B.A. (Hons.), Political Science, Indraprastha College For Women - University Of Delhi

In the modern interconnected world economy, global trade plays a crucial role in driving economic growth, fostering innovation, and facilitating cultural interactions. Nevertheless, this complex network of trade connections faces obstacles such as political rivalries, legal intricacies, and economic differences. This article examines and highlights the complex aspects of international trade law by analyzing case studies on trade disputes and investigating the root causes and consequences of them through it. It also analyzes the fundamental concepts of trade law, the methods for resolving trade conflicts, and the participation of important international organizations such as the World Trade Organization (WTO) in upholding the global trade regulations. The article also points out the difficulties in managing political, economic, and legal concerns in trade conflicts and the increasing impact of protectionist and economic nationalist policies. It highlights the importance of flexible and fair trade policies to tackle new issues such as digital commerce and sustainability. As the world economy changes, this article emphasizes the need to improve dialogues among multiple countries, improve ways to resolve conflicts, and promote trade agreements within regions to build a better global trading system that is more complete and strong. To sum up, this article supports a cooperative and future-oriented stance on global trade regulations, highlighting the importance of incorporating environmental criteria, balancing global integration with local concerns, and embracing technological progress. By successfully maneuvering through these challenges, global nations and individuals worldwide can strive towards creating a secure and thriving global economy.

AN OVERVIEW OF INDIA’S DIGITAL PERSONAL DATA PROTECTION ACT, 2023: KEY HIGHLIGHTS

Rachana D, B.B.A. LL.B, RV Institute of Legal Studies

The Digital Personal Data Protection Act, 2023 (DPDP Act) represents India’s legislative response to the challenges posed by rapid digitalization and increasing data breaches. Enacted to regulate digital services and protect privacy rights, the DPDP Act establishes a robust framework encompassing explicit consent requirements, rights for individuals over their data and stringent obligations for significant data fiduciaries (SDFs). Key provisions include the establishment of a Data Protection Board for oversight, penalties for non- compliance and exemptions for specific purposes like security and research.

REALITY IN FICTION: EXAMINING THE EFFECTS OF MEDIA VIOLENCE AND POTENTIAL FOR EMPATHY STUDIES

Sharyl Chin, English and Communication Studies (Concentration in Research), Nanyang Technological University

Since the inception of the Internet and the World Wide Web in the twentieth-century, the world has undergone a profound transformation in how information is shared, consumed, and accessed. The digital revolution has bolstered remote learning by democraticising information for varying audiences, and enhanced social connectivity for individuals across borders. Yet, the proliferation of content online has introduced numerous challenges that policymakers are struggling to address appropriately. One such issue is the concern over less desirable content online that vulnerable audiences, such as children, may inadvertently encounter. Violent media is an especially troubling example due to its potential to influence behaviour that harms social norms and its pervasive presence in mainstream media, including television shows, video games, comics, and more. Considering that research on media violence is one of the most extensively studied areas in media effects, this paper will provide an overview of the current research findings on media violence. Additionally, it will utilise VOID Interactive’s video game, Ready or Not (2023), as a case study of an underexplored aspect for researchers to consider – the role of empathy in moderating the effects of media violence. Through this dual approach, this essay aims to deepen current understandings of media violence and probe new directions for research that can better inform policy measures.